P112 Auto-titrating positive airway pressure in paediatric patients with obstructive sleep apnoea

Abstract Background Continuous positive airway pressure (CPAP) is the gold standard for treating obstructive sleep apnoea (OSA) in children. Standard practice involves in-laboratory titration polysomnography to determine the optimal treatment pressure for CPAP. Auto-titrating positive-airway-pressure (APAP) devices can automate this process. However, its use in children is not well studied. Methods Children receiving CPAP therapy for OSA were invited to participate in this study. They made two visits to the sleep laboratory within 4 weeks; the first was for CPAP titration, and the second was for unattended APAP titration. Parents/caretakers of participants completed the OSA-18 questionnaire during the second visit. Participant demographic and medical information was recorded. Optimal treatment pressures and polysomnography data from both visits were compared. Progress to date 2 children completed the pilot study; female (9 years) and male (15 years). Comparison by the sleep physician determined optimum CPAP pressure on the manual titration and APAP unattended titration being identical in the first case and 2cmH20 higher on the manual titration in the 2nd case. Recruitment and data analysis is ongoing. Intended Outcome and Impact Optimisation of treatment for paediatric OSA may become more accessible if it is found that APAP titration (unattended) is just as effective as CPAP titration (in-laboratory). Patient parameters identifying appropriate patients for APAP titration may also be determined from OSA-18 responses and medical history.