P107 Overnight Oximetry for the Diagnosis of Sleep-Disordered Breathing in Cervical Spinal Cord Injury Patients

Abstract Background Cervical Spinal Cord Injury (cSCI) patients have altered upper airway physiology and breathing mechanics, putting them at risk of clinically significant sleep-disordered breathing, including Obstructive Sleep Apnoea (OSA), Central Sleep Apnoea (CSA) and hypoventilation syndromes. However, polysomnography (PSG) for cSCI patients may be financially and environmentally costly and may not be accessible to all cSCI patients. Overnight oximetry is a portable and cost-effective alternative screening and diagnostic test, but its diagnostic accuracy has not been assessed in a cSCI population. Methods Patients will be eligible if they have sustained an acute cervical SCI between Jan 2021 and Dec 2023 and have undergone full PSG as an inpatient or outpatient within one year of their acute injury. Overnight oximetry from the night of the PSG will be compared to the overall PSG result for diagnostic accuracy with respect to OSA, CSA and hypoventilation. ROC analysis will be undertaken using metrics including ODI, time with SaO2 < 90%, as well as a clinician-based “pattern recognition” of the oximetry trace morphology. Progress to date 668 acute spinal cord admissions have been identified at a single tertiary spinal injury centre between Jan 2021 and Dec 2023. Work is ongoing to identify those patients with cervical SCI only and to analyse the oximetry and PSG data. Intended outcome and impact This study will help to standardise and streamline the diagnostic pathway for SDB in cSCI patients in a tertiary referral centre, and allow more time efficient access to therapy in this vulnerable patient group.