Multiple-breath washout is more sensitive than spirometry to detect lung function impairment in children and adults with bronchiectasis
LCI is more sensitive than FEV<sub>1</sub> to detect lung function impairment in bronchiectasis. These findings support further evaluation of LCI for clinical monitoring and as a sensitive outcome measure in clinical trials in people with bronchiectasis.
Authors
- Mehrak Yoosefi Moridani
- Carolin Meinus (ORCID: https://orcid.org/0000-0002-3659-8396)
- Stephanie A. Thee (ORCID: https://orcid.org/0000-0001-9090-7869)
- Olaf Schnabel
- Charlotte O. Pioch (ORCID: https://orcid.org/0009-0002-8636-9214)
- Jobst Roehmel (ORCID: https://orcid.org/0000-0002-1535-8852)
- Marcus Alexander Mall (ORCID: https://orcid.org/0000-0002-4057-2199)
- Susanne Lau (ORCID: https://orcid.org/0000-0002-5189-4265)
- Leonie Marie Busack (ORCID: https://orcid.org/0000-0001-5466-1793)
- Niklas Ziegahn (ORCID: https://orcid.org/0000-0003-4195-8584)
- Christine Allomba
- Mirjam Stahl (ORCID: https://orcid.org/0000-0001-6941-8315)
- Bent R. Fuhlrott (ORCID: https://orcid.org/0009-0004-9689-8691)
Institutions
- Association for Symbolic Logic (US)
- Humboldt-Universität zu Berlin (DE)
- Equilibrium Research (GB)
- German Center for Lung Research (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1183/23120541.00987-2024
- Citations
- 2
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung