Maresin1 Inhibits Ferroptosis via the Nrf2/SLC7A11/GPX4 Pathway to Protect Against Sepsis-Induced Acute Liver Injury
The results indicate that MaR1 mitigates SI-ALI via stimulating the Nrf2/SLC7A11/GPX4 pathway to suppress ferroptosis. Moreover, it offers significant potential as a new agent for the prevention of SI-ALI.
Authors
- Yongjie Yin (ORCID: https://orcid.org/0000-0002-5261-7753)
- Jingxiao Zhang (ORCID: https://orcid.org/0000-0003-0960-986X)
- Yongjing Guo
- Jian Sun (ORCID: https://orcid.org/0000-0002-6265-7898)
- Huimin Chen (ORCID: https://orcid.org/0000-0003-0329-8175)
Institutions
- Second Affiliated Hospital of Jilin University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/jir.s498775
- Citations
- 14
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 5.87