Clinicopathological characteristics of light chain proximal tubulopathy: a multicentre case series
Proteinuria and kidney dysfunction are the most common but less-specific renal manifestations of LCPTs, with most featuring Fanconi syndrome. Crystalline LCPT, primarily associated with κ-LC, is the predominant form. Most inclusions displayed intraindividual homogeneity and interindividual heterogeneity by electron microscopy. Most achieved haematological responses and favourable renal outcomes.
Authors
- Caihong Zeng (ORCID: https://orcid.org/0000-0002-3816-5164)
- Shi‐Hui Dong (ORCID: https://orcid.org/0000-0002-1743-2163)
- Guisen Li (ORCID: https://orcid.org/0000-0003-1970-9979)
- Ping Zhang (ORCID: https://orcid.org/0000-0002-4601-0779)
- Fan Yang (ORCID: https://orcid.org/0000-0003-0563-3395)
- Feng Xu (ORCID: https://orcid.org/0000-0002-1496-9141)
- Yujie Wang (ORCID: https://orcid.org/0000-0003-4457-8325)
- Feng Liu (ORCID: https://orcid.org/0000-0002-1074-2601)
- Shaojun Liu (ORCID: https://orcid.org/0000-0003-2433-8340)
- Xinchen Yao
- Yao Lin (ORCID: https://orcid.org/0000-0002-0493-0155)
- Xiaodong Zhu (ORCID: https://orcid.org/0000-0003-4345-5526)
- Mingchao Zhang
- Dandan Liang (ORCID: https://orcid.org/0000-0003-4639-8475)
- Ruimin Hu
- Guolan Xing
- Shaoshan Liang
Institutions
- Fudan University (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Huashan Hospital (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Journal of Clinical Pathology
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1136/jcp-2024-209620
- Citations
- 1
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- National Natural Science Foundation of China