Association between changes in thyroid hormones and incident type 2 diabetes using joint models of longitudinal and time-to-event data: more than a decade follow up in the Tehran thyroid study
The findings of this study suggest that dynamic changes in serum thyroid hormones are associated with the development of T2DM. Rising TSH and decreasing FT4 over time are associated with a lower risk of diabetes. These findings suggest a complex interplay between thyroid function and the risk of T2DM, emphasizing the importance of monitoring thyroid hormone levels as a part of T2DM prevention strategies.
Authors
- Alireza Amirabadizadeh (ORCID: https://orcid.org/0000-0002-2495-5042)
- Ladan Mehran (ORCID: https://orcid.org/0000-0001-8568-7419)
- Samaneh Asgari (ORCID: https://orcid.org/0000-0002-7032-310X)
- Fereidoun Azizi (ORCID: https://orcid.org/0000-0002-6470-2517)
- Davood Khalili (ORCID: https://orcid.org/0000-0003-4956-1039)
- Atieh Amouzegar (ORCID: https://orcid.org/0000-0003-1046-0003)
Institutions
- Research Institute for Endocrine Sciences (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-12-13
- DOI
- https://doi.org/10.3389/fendo.2024.1475286
- Citations
- 2
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.72