Microwave‐Assisted Synthesis of 2‐Aryl‐5,6,7,8‐tetrahydrobenzo[4,5]thieno[2,3‐ <i>d</i> ]pyrimidinones
Abstract Herein, a protocol for the synthesis of 2‐aryl‐5,6,7,8‐tetrahydrobenzo[4,5]thieno[2,3‐ d ]pyrimidinones is presented in two‐step. The precursor is prepared from inexpensive and readily available starting materials in high yield. Then, the desired products have been prepared using both conventional and microwave irradiation methods in presence of HCl as catalyst. It resulted that the microwave irradiation gave very lower reaction time and higher yields compared to the conventional method.
Authors
- Hossein Mehrabi
- Farzaneh Alizadeh‐Bami
- Soheil Alinaghi‐Langari
Institutions
- Vali Asr University of Rafsanjan (IR)
Publication Details
- Journal
- ChemistrySelect
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/slct.202404000
- Citations
- 2
- Primary Topic
- Multicomponent Synthesis of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 0.50