Microwave‐Assisted Synthesis of 2‐Aryl‐5,6,7,8‐tetrahydrobenzo[4,5]thieno[2,3‐ <i>d</i> ]pyrimidinones

Abstract Herein, a protocol for the synthesis of 2‐aryl‐5,6,7,8‐tetrahydrobenzo[4,5]thieno[2,3‐ d ]pyrimidinones is presented in two‐step. The precursor is prepared from inexpensive and readily available starting materials in high yield. Then, the desired products have been prepared using both conventional and microwave irradiation methods in presence of HCl as catalyst. It resulted that the microwave irradiation gave very lower reaction time and higher yields compared to the conventional method.

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Publication Details

Journal
ChemistrySelect
Published
2024-12-01
DOI
https://doi.org/10.1002/slct.202404000
Citations
2
Primary Topic
Multicomponent Synthesis of Heterocycles
Type
article
Field-Weighted Citation Impact
0.50
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article

Microwave‐Assisted Synthesis of 2‐Aryl‐5,6,7,8‐tetrahydrobenzo[4,5]thieno[2,3‐ d ]pyrimidinones

Hossein Mehrabi, Farzaneh Alizadeh‐Bami, Soheil Alinaghi‐Langari
2 citations
ChemistrySelect
Multicomponent Synthesis of Heterocycles
0.50
article

Microwave‐Assisted Synthesis of 2‐Aryl‐5,6,7,8‐tetrahydrobenzo[4,5]thieno[2,3‐ d ]pyrimidinones

Hossein Mehrabi, Farzaneh Alizadeh‐Bami, Soheil Alinaghi‐Langari
article en
2 citations

Abstract

Abstract Herein, a protocol for the synthesis of 2‐aryl‐5,6,7,8‐tetrahydrobenzo[4,5]thieno[2,3‐ d ]pyrimidinones is presented in two‐step. The precursor is prepared from inexpensive and readily available starting materials in high yield. Then, the desired products have been prepared using both conventional and microwave irradiation methods in presence of HCl as catalyst. It resulted that the microwave irradiation gave very lower reaction time and higher yields compared to the conventional method.

ChemistrySelectVol. 9(47)
Vali Asr University of Rafsanjan (IR)
Openalex Percentile: Top 37%
Multicomponent Synthesis of Heterocycles
0.50
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