Comparative analysis of mineralocorticoid receptor antagonists and renin-angiotensin system inhibitors/angiotensin receptor neprilysin inhibitor in heart failure with mildly reduced ejection fraction
MRA had a neutral effect on cardiovascular death and HHF, while RASI/ARNI was associated with a lower risk of cardiovascular death. RASI/ARNI may be more beneficial than MRA for HFmrEF patients. Regular re-evaluation is essential to adjust heart failure treatment.
Authors
- Kai-Chun Chang (ORCID: https://orcid.org/0000-0001-9215-3108)
- Jen‐Fang Cheng (ORCID: https://orcid.org/0000-0001-9729-5551)
- Lian‐Yu Lin (ORCID: https://orcid.org/0000-0001-7505-6429)
- Ting‐Tse Lin (ORCID: https://orcid.org/0000-0002-8810-5127)
- Zheng‐Wei Chen (ORCID: https://orcid.org/0000-0001-7728-6674)
- Cho‐Kai Wu (ORCID: https://orcid.org/0000-0002-3867-150X)
- David Kuan
- Chia-Chen Lee
Institutions
- Fu Jen Catholic University (TW)
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
- National Yunlin University of Science and Technology (TW)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-12-13
- DOI
- https://doi.org/10.3389/fphar.2024.1507326
- Citations
- 2
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Taiwan University Hospital
- National Taiwan University