Association between 25(OH) vitamin D and schizophrenia: shared genetic correlation, pleiotropy, and causality
Our study identifies NEK4 as a potential therapeutic target and highlights the involvement of hyaluronan metabolism in the genetic association between 25OHD and SCZ. These findings provide valuable insights into shared genetic pathways, immune-related connections, and causal interactions in the context of SCZ.
Authors
- Mingzhu Su (ORCID: https://orcid.org/0000-0001-9299-648X)
- Xiaomin Li (ORCID: https://orcid.org/0000-0001-6056-6928)
- Yi Jin
- Huimin Lu
- Guo-Wei Rong
Institutions
- Jiangsu University (CN)
- Xuzhou Medical College (CN)
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-12-13
- DOI
- https://doi.org/10.3389/fnut.2024.1415132
- Citations
- 2
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Xuzhou Medical University
- Jiangsu Province Key Laboratory of Anesthesiology