Nanoformulation Of Vitamin D Derivatives and Metabolites

The goal of this research is to improve the bioavailability and therapeutic effectiveness of vitamin D derivatives and metabolites by creating nanoformulations that encapsulate them. We created nanoparticles with advantageous physicochemical characteristics, such as ideal particle size and encapsulation efficiency, by applying cutting-edge nanoengineering techniques. Under physiological conditions, sustained release profiles were found using in vitro release kinetics. Stability tests verified resilience to environmental influences, while cytotoxicity evaluations showed safety for pertinent cell lines. According to the results, tailored nanoformulations could be useful tactics for enhancing the distribution of vitamin D, treating deficiencies, and broadening the range of therapeutic uses.

Authors

Publication Details

Journal
African Journal of Biomedical Research
Published
2024-09-20
DOI
https://doi.org/10.53555/ajbr.v27i4s.4897
Primary Topic
Vitamin D Research Studies
Type
article
Field-Weighted Citation Impact
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article

Nanoformulation Of Vitamin D Derivatives and Metabolites

Ranjit Ingole
African Journal of Biomedical Research
Vitamin D Research Studies
article

Nanoformulation Of Vitamin D Derivatives and Metabolites

Ranjit Ingole
article en

Abstract

The goal of this research is to improve the bioavailability and therapeutic effectiveness of vitamin D derivatives and metabolites by creating nanoformulations that encapsulate them. We created nanoparticles with advantageous physicochemical characteristics, such as ideal particle size and encapsulation efficiency, by applying cutting-edge nanoengineering techniques. Under physiological conditions, sustained release profiles were found using in vitro release kinetics. Stability tests verified resilience to environmental influences, while cytotoxicity evaluations showed safety for pertinent cell lines. According to the results, tailored nanoformulations could be useful tactics for enhancing the distribution of vitamin D, treating deficiencies, and broadening the range of therapeutic uses.

African Journal of Biomedical Research
Zero hunger
Openalex Percentile: Top 62%
Vitamin D Research Studies
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