Schiff BaseMetal Chloride Complexes of Dapsone andPyridine-2-CarboxaldehydeTheir Synthesis, Characterization And Antifungal Properties

Schiff bases have been the subject of much research due to their important bioactivities, active azomethine (-N=CH-) pharmacophore, is structurally similar to naturally occurring biological compounds, have selectivity, sensitivity and synthetic flexibility to the central metal atom [1-2]. In present paper we will synthesize Schiff base by condensing Dapsone with Pyridine -2-carboxaldehyde. Then Schiff base formed was complexed with metal ions. IR, elemental analysis, UV, M.P were used to analyse the complexes. Then evaluate their biological properties. Biological properties of metal complexes were greater than that of Dapsone and Schiff base of Dapsone with Pyridine-2-carboxaldehye.    

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Publication Details

Journal
African Journal of Biomedical Research
Published
2024-12-13
DOI
https://doi.org/10.53555/ajbr.v28i1.4875
Primary Topic
Metal complexes synthesis and properties
Type
article
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article

Schiff BaseMetal Chloride Complexes of Dapsone andPyridine-2-CarboxaldehydeTheir Synthesis, Characterization And Antifungal Properties

Monika Monika
African Journal of Biomedical Research
Metal complexes synthesis and properties
article

Schiff BaseMetal Chloride Complexes of Dapsone andPyridine-2-CarboxaldehydeTheir Synthesis, Characterization And Antifungal Properties

Monika Monika
article en

Abstract

Schiff bases have been the subject of much research due to their important bioactivities, active azomethine (-N=CH-) pharmacophore, is structurally similar to naturally occurring biological compounds, have selectivity, sensitivity and synthetic flexibility to the central metal atom [1-2]. In present paper we will synthesize Schiff base by condensing Dapsone with Pyridine -2-carboxaldehyde. Then Schiff base formed was complexed with metal ions. IR, elemental analysis, UV, M.P were used to analyse the complexes. Then evaluate their biological properties. Biological properties of metal complexes were greater than that of Dapsone and Schiff base of Dapsone with Pyridine-2-carboxaldehye.    

African Journal of Biomedical Research
Openalex Percentile: Top 60%
Metal complexes synthesis and properties
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