Identification and verification of the optimal feature genes of ferroptosis in thyroid-associated orbitopathy
Through bioinformatics analysis, this study identified and validated two OFGs of ferroptosis with diagnostic and therapeutic potential in TAO orbital adipose tissue, suggesting that the downregulation of ACO1 and HCAR1 may be potential molecular targets in the pathogenesis of TAO.
Authors
- Yaohua Wang (ORCID: https://orcid.org/0000-0002-8571-5472)
- Puying Gan
- Yunxiu Chen
- Qihua Xu (ORCID: https://orcid.org/0000-0001-9976-9159)
- Hongfei Liao (ORCID: https://orcid.org/0000-0003-1955-6570)
- Xuemei Li (ORCID: https://orcid.org/0000-0003-4120-0589)
- Qi Jin (ORCID: https://orcid.org/0000-0002-6536-621X)
- Siyi Wang (ORCID: https://orcid.org/0000-0003-0304-9398)
- Jinhai Yu
- Chao Xiong (ORCID: https://orcid.org/0000-0003-2042-2983)
- Zhangjun Ren
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-13
- DOI
- https://doi.org/10.3389/fimmu.2024.1422497
- Citations
- 4
- Primary Topic
- Clusterin in disease pathology
- Type
- article
- Field-Weighted Citation Impact
- 1.13