Frequency, characteristics, and immunological accompaniments of ataxia in anti-NMDAR antibody-associated encephalitis
Ataxia of different types is quite common in NMDAR-E. Cerebellar ataxia in NMDAR-E is mostly transient. NMDAR-E followed by persistent ataxia and cerebellar atrophy is very rare. Cerebellar ataxia in NMDAR-E may not be explained by concomitant KLHL11, MOG, AQP-4, or GluK2 autoimmunity. Of note, ataxia in NMDAR-E may result from treatment complications and, most interestingly, from MS manifesting in temporal association with NMDAR-E.
Authors
- Hauke Schneider (ORCID: https://orcid.org/0000-0002-9641-0922)
- Jan Lewerenz (ORCID: https://orcid.org/0000-0002-9272-529X)
- Robert Markewitz
- Martin Lesser (ORCID: https://orcid.org/0000-0002-0318-5739)
- Albrecht Günther (ORCID: https://orcid.org/0000-0002-2394-3947)
- Manuel Alexander Friese (ORCID: https://orcid.org/0000-0001-6380-2420)
- Frank Leypoldt (ORCID: https://orcid.org/0000-0002-8972-515X)
- Lídia Sabater (ORCID: https://orcid.org/0000-0001-8556-6166)
- Annika Kather
- Klaus‐Peter Wandinger (ORCID: https://orcid.org/0000-0002-5483-4276)
- Sarah Jesse (ORCID: https://orcid.org/0000-0001-6235-8145)
- Marius Ringelstein (ORCID: https://orcid.org/0000-0003-3618-8407)
- Franziska Thaler
- Philipp Schwenkenbecher (ORCID: https://orcid.org/0000-0002-1260-1650)
- Niklas Vogel (ORCID: https://orcid.org/0009-0004-1461-2419)
- Kurt‐Wolfram Sühs (ORCID: https://orcid.org/0000-0002-8077-481X)
- Katharina Wurdack (ORCID: https://orcid.org/0000-0003-0952-5658)
- Nico Melzer (ORCID: https://orcid.org/0000-0002-2420-701X)
- Joseph Kuchling (ORCID: https://orcid.org/0000-0002-7981-2073)
- Justina Dargvainiene (ORCID: https://orcid.org/0009-0002-4114-3748)
- Carsten Finke (ORCID: https://orcid.org/0000-0002-7665-1171)
- Lena Kristina Pfeffer (ORCID: https://orcid.org/0000-0003-3057-6492)
- Jonathan Wickel (ORCID: https://orcid.org/0000-0002-5854-3759)
- Christian Geis (ORCID: https://orcid.org/0000-0002-9859-581X)
- Marc Riemann
- Dominica Hudasch
Institutions
- Universität Hamburg (DE)
- University of Augsburg (DE)
- LMU Klinikum (DE)
- Medizinische Hochschule Hannover (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- University Hospital Schleswig-Holstein (DE)
- Jena University Hospital (DE)
- University Hospital Ulm (DE)
- Fundació Clínic per a la Recerca Biomèdica (ES)
- University Hospital Carl Gustav Carus (DE)
- Heinrich Heine University Düsseldorf (DE)
- Universitat de Barcelona (ES)
- Charité - Universitätsmedizin Berlin (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-13
- DOI
- https://doi.org/10.3389/fimmu.2024.1500904
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00