The combination of decitabine with multi-omics confirms the regulatory pattern of the correlation between DNA methylation of the CACNA1C gene and atrial fibrillation

The DNA methylation levels at three CpG sites in intron 30 of the CACNA1C gene are associated with AF status, and potentially regulated by ATF7IP and KAT2B.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2024-12-13
DOI
https://doi.org/10.3389/fphar.2024.1497977
Primary Topic
Cancer-related gene regulation
Type
article
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article

The combination of decitabine with multi-omics confirms the regulatory pattern of the correlation between DNA methylation of the CACNA1C gene and atrial fibrillation

Siyuan Niu, Xiaozhong Peng, Xiaoning Liu, Caixia Shao et al.
Frontiers in Pharmacology
Cancer-related gene regulation
article

The combination of decitabine with multi-omics confirms the regulatory pattern of the correlation between DNA methylation of the CACNA1C gene and atrial fibrillation

Siyuan Niu, Xiaozhong Peng, Xiaoning Liu, Caixia Shao, Qijun Li, Heng Yang, Xiangguang Meng, Yuling Yang
article en

Abstract

The DNA methylation levels at three CpG sites in intron 30 of the CACNA1C gene are associated with AF status, and potentially regulated by ATF7IP and KAT2B.

Frontiers in PharmacologyVol. 15
Daqing Oilfield General Hospital (CN), Zhengzhou People's Hospital (CN), Huanghe Science and Technology College (CN)
Good health and well-being
Openalex Percentile: Top 80%
Cancer-related gene regulation
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