Recombinant characteristics and pathogenicity of a novel PRRSV variant in weaned piglets derived from recombination of three clinical epidemic strains
The findings indicate that the novel crossbred PRRSV isolate SDVD-NMG2023, derived from three prevalent clinical strains, may induce more unusual clinical presentations compared to those associated with HP-PRRS, albeit still impacting the health of the herd by causing immunosuppression. This study provides critical insights into the emergence of multi-strain PRRSV recombination, particularly between NADC30/34-like and HP-PRRSV-like strains, supporting a more strategic and comprehensive approach to PRRS prevention and control.
Authors
- Ying Yu (ORCID: https://orcid.org/0000-0002-4524-0791)
- Xinnian Dong (ORCID: https://orcid.org/0000-0002-1120-0951)
- Luming Yao (ORCID: https://orcid.org/0000-0002-9417-4356)
- Gang Wang (ORCID: https://orcid.org/0000-0002-5842-8080)
- Xinyuan Wang (ORCID: https://orcid.org/0000-0002-3107-8359)
- Yalin Yang
Institutions
- Qingdao Agricultural University (CN)
- Shandong Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2024-12-13
- DOI
- https://doi.org/10.3389/fvets.2024.1496316
- Citations
- 2
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.68
Funders
- Qingdao Agricultural University
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province