β-caryophyllene sensitizes hepatocellular carcinoma cells to chemotherapeutics and inhibits cell malignancy through targeting MAPK signaling pathway
BCP inhibits malignant properties of HCC and synergistically sensitizes the anticancer activity of DOX and DDP. In HCC cells, BCP primarily targets the PGF gene and MAPK signaling pathway.
Authors
- Guangchao Sui (ORCID: https://orcid.org/0000-0002-8164-5585)
- Cheng Du (ORCID: https://orcid.org/0000-0003-0213-9199)
- Najeeb Ullah (ORCID: https://orcid.org/0000-0003-0900-5927)
- Hai Wang (ORCID: https://orcid.org/0000-0003-2063-2008)
- Shah Jehan (ORCID: https://orcid.org/0009-0003-8490-9536)
- Irum Basheer
- Dangdang Li (ORCID: https://orcid.org/0000-0001-6407-9705)
- Guangyue Li (ORCID: https://orcid.org/0009-0003-7189-5796)
- Ali Raza
Institutions
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Zhejiang Lab (CN)
- Northeast Forestry University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-12-13
- DOI
- https://doi.org/10.3389/fphar.2024.1492670
- Citations
- 7
- Primary Topic
- Plant biochemistry and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- National Natural Science Foundation of China