Evaluation of fibroinflammatory activity in thyroid eye disease using [18F]AlF-NOTA-FAPI-04 PET/CT: A prospective study
The diffuse high FAPI uptake with excellent TBR in the EOMs could illustrate the activity of TED, positively correlated with pathological fibroinflammatory scores. These findings suggest that [<sup>18</sup>F]AlF-NOTA-FAPI-04 PET/CT may serve as a promising reliable non-invasive approach for assessing disease activity in TED, potentially superior to the CAS.
Authors
- Yansong Lin (ORCID: https://orcid.org/0000-0001-6095-4728)
- Yinghong Zhang (ORCID: https://orcid.org/0000-0001-6805-7917)
- Lingge Suo (ORCID: https://orcid.org/0000-0002-4196-8224)
- Zhaofei Liu (ORCID: https://orcid.org/0000-0001-8718-8154)
- Lê Hữu Song (ORCID: https://orcid.org/0000-0003-2056-8499)
- Weifang Zhang (ORCID: https://orcid.org/0000-0003-3879-1285)
- Jichao Zhou
- Huanwen Wu (ORCID: https://orcid.org/0000-0002-3996-3176)
- Ningli Wang (ORCID: https://orcid.org/0000-0002-8933-4482)
- Hui Li (ORCID: https://orcid.org/0000-0003-2846-1602)
- Meixin Zhao
- Yi-Xiang Wang (ORCID: https://orcid.org/0000-0002-4021-4228)
- Debo You
- Chun Zhang (ORCID: https://orcid.org/0000-0001-7041-6958)
- Meng Wang (ORCID: https://orcid.org/0000-0001-7648-9955)
Institutions
- Beijing Tongren Hospital (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Peking Union Medical College Hospital (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1007/s00259-024-07015-y
- Citations
- 6
- Primary Topic
- Ophthalmology and Eye Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.55
Funders
- National Natural Science Foundation of China
- Peking University
- Peking University Third Hospital