Vaspin inhibits ferroptosis: A new hope for treating myocardial ischemia–reperfusion injury
Vaspin inhibits ferroptosis and upregulates the HIF-1α signaling pathway to mitigate myocardial I/R injury. The vaspin/HIF-1α pathway could be a potential target for MIRI prevention and treatment and offers fresh perspectives on ischemic heart disease management. Vaspin could be a novel cardioprotective agent that plays a significant role in the prevention and treatment of cardiovascular diseases.
Authors
- Xianqing Meng (ORCID: https://orcid.org/0009-0002-2414-9187)
- Laiyun Xin (ORCID: https://orcid.org/0000-0002-5355-1733)
- Duo Chen (ORCID: https://orcid.org/0000-0002-7816-8618)
- Xuehong Lin
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- CytoJournal
- Published
- 2024-12-13
- DOI
- https://doi.org/10.25259/cytojournal_141_2024
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.26