Endocrine effects of MEK and BRAF inhibitor therapy in paediatric patients: a tertiary centre experience
Clinicians using such treatments need to be aware of these potential effects, particularly the risk of hyponatraemia in patients with pre-existing central diabetes insipidus and monitor for these accordingly, including performing measurements of sodium and glucose prior to, during and after treatment.
Authors
- Harriet Gunn (ORCID: https://orcid.org/0000-0002-7161-6297)
- Buddhi Gunasekara (ORCID: https://orcid.org/0000-0003-4708-1015)
- Arif Hanafi Bin Jalal (ORCID: https://orcid.org/0000-0001-8909-9948)
- Hoong‐Wei Gan (ORCID: https://orcid.org/0000-0001-6198-0397)
Institutions
- University College London Hospitals NHS Foundation Trust (GB)
- Great Ormond Street Hospital (GB)
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- University College London (GB)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1007/s11060-024-04896-9
- Citations
- 3
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.31