The bile acid metabolome in umbilical cord blood and meconium of healthy newborns: distinct characteristics and implications
The bile acid metabolites in umbilical cord blood and meconium differ significantly, and the downstream bile acid metabolites in meconium are predominantly correlated with their upstream bile acids in meconium, but not those bile acids in umbilical cord blood. These findings contribute to a better understanding of bile acid metabolism <i>in utero</i> and lay the foundation for future research in this topic.
Authors
- Yujiao Zhang (ORCID: https://orcid.org/0000-0003-3217-8615)
- Xiaoping Lei (ORCID: https://orcid.org/0000-0003-3818-7117)
- Chunxia Lü (ORCID: https://orcid.org/0000-0003-1986-1188)
- Zhiyong Gao (ORCID: https://orcid.org/0000-0002-2181-7402)
- Ke Du (ORCID: https://orcid.org/0000-0002-3975-0314)
- Wenbin Dong (ORCID: https://orcid.org/0000-0001-7480-5547)
- Die Xu
- Siqi Zhang (ORCID: https://orcid.org/0009-0008-7557-9244)
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2024-12-13
- DOI
- https://doi.org/10.7717/peerj.18506
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Southwest Medical University
- Affiliated Hospital of Southwest Medical University