Periodontal manifestations in neurofibromatosis type 1: A case report

Neurofibromatosis type 1 (NF1), also known as Von Recklinghausen’s disease, is an autosomal dominant disorder first described by Von Recklinghausen. With a prevalence of 1 in 2,200 to 3,000 births, NF1 frequently includes both cutaneous and oral manifestations. Oral symptoms appear in 72-92% of cases, predominantly affecting the tongue and buccal mucosa. This case report discusses a 30-year-old male presenting with NF1, characterized by multiple faint skin lesions, periodic chest pain, and a rare instance of generalized aggressive periodontitis. The diagnostic approach incorporated clinical and radiographic assessments, which revealed distinct periodontal involvement uncommon in NF1 cases. This report aims to raise awareness of the periodontal features associated with NF1, underscoring the importance for dental professionals in managing such cases.