188P Single-cell and spatial transcriptomics delineate the microstructure and immune landscape of intrahepatic cholangiocarcinoma in the leading-edge area

Background: Currently anti-PD(L)1 immunotherapy is widely used to treat microsatellite-instability-high (MSI-H) pan-cancers.However, part of MSI-H patients and more others with microsatellite stable (MSS) phenotype do not respond well to this immunotherapy, which means potential extra factors or signals have also participated in the complicated tumor microevironment.

Authors

Publication Details

Journal
Immuno-Oncology Technology
Published
2024-12-01
DOI
https://doi.org/10.1016/j.iotech.2024.100941
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
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article

188P Single-cell and spatial transcriptomics delineate the microstructure and immune landscape of intrahepatic cholangiocarcinoma in the leading-edge area

Zhong Li
Immuno-Oncology Technology
Cholangiocarcinoma and Gallbladder Cancer Studies
article

188P Single-cell and spatial transcriptomics delineate the microstructure and immune landscape of intrahepatic cholangiocarcinoma in the leading-edge area

Zhong Li
article en

Abstract

Background: Currently anti-PD(L)1 immunotherapy is widely used to treat microsatellite-instability-high (MSI-H) pan-cancers.However, part of MSI-H patients and more others with microsatellite stable (MSS) phenotype do not respond well to this immunotherapy, which means potential extra factors or signals have also participated in the complicated tumor microevironment.

Immuno-Oncology TechnologyVol. 24
Life in Land
Openalex Percentile: Top 57%
Cholangiocarcinoma and Gallbladder Cancer Studies
DOIOpen Access PDFOpenAlex
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188P Single-cell and spatial transcriptomics delineate the microstructure and immune landscape of intrahepatic cholangiocarcinoma in the leading-edge area — Zhong Li · Immuno-Oncology Technology (2024) | TGRS Research Map | TGRS