187P Single-cell RNA sequencing elucidates the role of intercommunication between epithelial cells, immune cells, and fibroblasts in high-grade serous ovarian cancer
Background: Currently anti-PD(L)1 immunotherapy is widely used to treat microsatellite-instability-high (MSI-H) pan-cancers.However, part of MSI-H patients and more others with microsatellite stable (MSS) phenotype do not respond well to this immunotherapy, which means potential extra factors or signals have also participated in the complicated tumor microevironment.
Authors
- Meiling Jiang (ORCID: https://orcid.org/0000-0001-9985-3510)
- Yong Teng (ORCID: https://orcid.org/0000-0002-1856-7289)
- W. Yue (ORCID: https://orcid.org/0009-0009-9604-1483)
- Xue Zhao (ORCID: https://orcid.org/0000-0003-3111-9648)
Publication Details
- Journal
- Immuno-Oncology Technology
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1016/j.iotech.2024.100940
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00