Tenosynovitis with psammomatous calcification—Analysis by scanning electron microscopy and energy‐dispersive x‐ray spectroscopy

Tenosynovitis with psammomatous calcification (TPC) is an extremely rare condition. It was first described as a characteristic subtype of idiopathic calcifying tenosynovitis, with only 40 cases reported to date. Here, we present a case of TPC affecting a female patient in her late teens, with no relevant medical history. She presented with discomfort and pain in the right first toe. A 10-mm mushroom-like calcified mass was observed in the metatarsophalangeal joint on radiographs. The surgical specimen revealed chronic synovitis with calcification. Numerous psammomatous bodies are observed in the synovium, often with granulomatous reactions. After removal of the mass, no recurrence has been observed for 5 years. Although the etiology of TPC has been suggested to be related to repetitive trauma to the tendon or peritendinous soft tissue, the composition and mechanism of calcification remain unclear because of its rarity. In this report, we also discuss the calcification mechanism in TPC, supported by scanning electron microscopy and energy-dispersive x-ray spectroscopy findings.

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Publication Details

Journal
Pathology International
Published
2024-12-13
DOI
https://doi.org/10.1111/pin.13502
Citations
1
Primary Topic
Musculoskeletal synovial abnormalities and treatments
Type
article
Field-Weighted Citation Impact
0.47
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Tenosynovitis with psammomatous calcification—Analysis by scanning electron microscopy and energy‐dispersive x‐ray spectroscopy

Yuta Sonobe, Kazuaki Hashimoto, Hiromasa Hasegawa, Hisatake Takamiya et al.
1 citations
Pathology International
Musculoskeletal synovial abnormalities and treatments
0.47
article

Tenosynovitis with psammomatous calcification—Analysis by scanning electron microscopy and energy‐dispersive x‐ray spectroscopy

Yuta Sonobe, Kazuaki Hashimoto, Hiromasa Hasegawa, Hisatake Takamiya, Eiichi Konishi, Y Yamawaki
article en
1 citations

Abstract

Tenosynovitis with psammomatous calcification (TPC) is an extremely rare condition. It was first described as a characteristic subtype of idiopathic calcifying tenosynovitis, with only 40 cases reported to date. Here, we present a case of TPC affecting a female patient in her late teens, with no relevant medical history. She presented with discomfort and pain in the right first toe. A 10-mm mushroom-like calcified mass was observed in the metatarsophalangeal joint on radiographs. The surgical specimen revealed chronic synovitis with calcification. Numerous psammomatous bodies are observed in the synovium, often with granulomatous reactions. After removal of the mass, no recurrence has been observed for 5 years. Although the etiology of TPC has been suggested to be related to repetitive trauma to the tendon or peritendinous soft tissue, the composition and mechanism of calcification remain unclear because of its rarity. In this report, we also discuss the calcification mechanism in TPC, supported by scanning electron microscopy and energy-dispersive x-ray spectroscopy findings.

Pathology InternationalVol. 75(2)
Kyoto Prefectural University of Medicine (JP), Shinshu University Hospital (JP), Tane General Hospital (JP)
Openalex Percentile: Top 29%
Musculoskeletal synovial abnormalities and treatments
0.47
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Tenosynovitis with psammomatous calcification—Analysis by scanning electron microscopy and energy‐dispersive x‐ray spectroscopy — Yuta Sonobe, Kazuaki Hashimoto, et al. · Pathology International (2024) | TGRS Research Map | TGRS