A Zeolitic Imidazolate Framework-Based Antimicrobial Peptide Delivery System with Enhanced Anticancer Activity and Low Systemic Toxicity

The CEC@ZIF-8 nano-drug delivery system significantly enhanced the anti-cervical cancer effect of CEC both in vivo and in vitro, providing a more promising drug delivery system for clinical applications and tumor management. At the same time, this work demonstrates the clinical potential of CEC-loaded ZIF-8 nanoparticles for the selective destruction of tumor tissues.

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Publication Details

Journal
Pharmaceutics
Published
2024-12-13
DOI
https://doi.org/10.3390/pharmaceutics16121591
Citations
4
Primary Topic
Peptidase Inhibition and Analysis
Type
article
Field-Weighted Citation Impact
1.13

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article

A Zeolitic Imidazolate Framework-Based Antimicrobial Peptide Delivery System with Enhanced Anticancer Activity and Low Systemic Toxicity

Jinyao Li, Lijie Xia, Jingwen Jiang, Yanzhu Pan et al.
4 citations
Pharmaceutics
Peptidase Inhibition and Analysis
1.13
article

A Zeolitic Imidazolate Framework-Based Antimicrobial Peptide Delivery System with Enhanced Anticancer Activity and Low Systemic Toxicity

Jinyao Li, Lijie Xia, Jingwen Jiang, Yanzhu Pan, Kaderya Kaysar
article en
4 citations

Abstract

The CEC@ZIF-8 nano-drug delivery system significantly enhanced the anti-cervical cancer effect of CEC both in vivo and in vitro, providing a more promising drug delivery system for clinical applications and tumor management. At the same time, this work demonstrates the clinical potential of CEC-loaded ZIF-8 nanoparticles for the selective destruction of tumor tissues.

PharmaceuticsVol. 16(12)
Xinjiang University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 18%
Peptidase Inhibition and Analysis
1.13
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