A Zeolitic Imidazolate Framework-Based Antimicrobial Peptide Delivery System with Enhanced Anticancer Activity and Low Systemic Toxicity
The CEC@ZIF-8 nano-drug delivery system significantly enhanced the anti-cervical cancer effect of CEC both in vivo and in vitro, providing a more promising drug delivery system for clinical applications and tumor management. At the same time, this work demonstrates the clinical potential of CEC-loaded ZIF-8 nanoparticles for the selective destruction of tumor tissues.
Authors
- Jinyao Li (ORCID: https://orcid.org/0000-0002-3295-6096)
- Lijie Xia (ORCID: https://orcid.org/0000-0002-0411-246X)
- Jingwen Jiang (ORCID: https://orcid.org/0009-0006-9768-0314)
- Yanzhu Pan
- Kaderya Kaysar
Institutions
- Xinjiang University (CN)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2024-12-13
- DOI
- https://doi.org/10.3390/pharmaceutics16121591
- Citations
- 4
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.13
Funders
- National Natural Science Foundation of China