Mechanism of Zhengsui Wan in the Treatment of Acute Lymphoblastic Leukemia Based on Network Pharmacology and Experimental Validation
In this study, we successfully identified possible active ingredients and predicted potential targets and pathways for ZSW for the treatment of ALL. We provide a new strategy for further research on the molecular basis of ZSW biological effects in ALL. In addition, the potential active ingredients could provide new leads for drug discovery in ALL investigations.
Authors
- Chenyang Fan (ORCID: https://orcid.org/0000-0002-3425-7352)
- Xia Tao (ORCID: https://orcid.org/0000-0001-8466-1196)
- Ning Ji (ORCID: https://orcid.org/0009-0004-3200-9429)
- D Li
- Juan Xie (ORCID: https://orcid.org/0000-0002-7841-6749)
- Weilong Sun (ORCID: https://orcid.org/0000-0002-8281-5056)
- Peng Yuan (ORCID: https://orcid.org/0000-0002-5660-225X)
- Lijun Fang (ORCID: https://orcid.org/0000-0002-2653-9034)
- Xiangdong Yang (ORCID: https://orcid.org/0000-0003-2650-1885)
- Fujun Yang
Institutions
- University of International Business and Economics (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Current Stem Cell Research & Therapy
- Published
- 2024-12-13
- DOI
- https://doi.org/10.2174/011574888x327937241129062944
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00