Investigation of integron gene cassettes in trimethoprim-sulfamethoxazole-resistant Acinetobacter baumannii isolates

Despite the low integron detection in the resistant isolates, with the detection of class I and class II integrons among A. baumannii isolates, it was determined that HAIs could spread very rapidly within the hospital and cause multidrug resistance. This study reveals the need for comprehensive surveillance and molecular characterization of integron-mediated resistance mechanisms to inform effective strategies to combat infections caused by multidrug-resistant (MDR) A. baumannii.

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Publication Details

Journal
Advances in Clinical and Experimental Medicine
Published
2024-12-13
DOI
https://doi.org/10.17219/acem/191058
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
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article

Investigation of integron gene cassettes in trimethoprim-sulfamethoxazole-resistant Acinetobacter baumannii isolates

Elif Sevi̇m, Cihat ÖZTÜRK, Rukiye Akyol, Sadık Küçükgünay
Advances in Clinical and Experimental Medicine
Antibiotic Resistance in Bacteria
article

Investigation of integron gene cassettes in trimethoprim-sulfamethoxazole-resistant Acinetobacter baumannii isolates

Elif Sevi̇m, Cihat ÖZTÜRK, Rukiye Akyol, Sadık Küçükgünay
article en

Abstract

Despite the low integron detection in the resistant isolates, with the detection of class I and class II integrons among A. baumannii isolates, it was determined that HAIs could spread very rapidly within the hospital and cause multidrug resistance. This study reveals the need for comprehensive surveillance and molecular characterization of integron-mediated resistance mechanisms to inform effective strategies to combat infections caused by multidrug-resistant (MDR) A. baumannii.

Advances in Clinical and Experimental MedicineVol. 34(7)
Ministry of Health (TR), Ahi Evran University (TR)
Openalex Percentile: Top 85%
Antibiotic Resistance in Bacteria
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