Spatial analyses revealed CXCL5 and SLC6A14 as the markers of microvascular invasion in intrahepatic cholangiocarcinoma
This study identifies CXCL5 and SLC6A14 as key biomarkers of MVI, highlighting their roles in tumor proliferation, immune resistance, and poor clinical outcomes. These findings provide valuable insights into the spatial organization of MVI and its contribution to ICC progression, offering potential therapeutic targets.
Authors
- Xiaohong Han (ORCID: https://orcid.org/0000-0001-9190-0167)
- Le Tang (ORCID: https://orcid.org/0000-0002-5192-3329)
- Tongji Xie (ORCID: https://orcid.org/0000-0002-3276-9645)
- Guangyu Fan (ORCID: https://orcid.org/0000-0003-1561-0007)
- Yuankai Shi (ORCID: https://orcid.org/0000-0002-3342-4964)
- Lin Li (ORCID: https://orcid.org/0000-0002-4932-6488)
- Liyuan Dai (ORCID: https://orcid.org/0009-0007-4848-3709)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1097/hc9.0000000000000597
- Citations
- 3
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.72