Vessels encapsulating tumor clusters contribute to the intratumor heterogeneity of HCC on Gd-EOB-DTPA–enhanced MRI
VETC is associated with local reductions of both AVD and OATP1B3 expression, likely contributing to heterogeneous enhancement patterns in EOB-MRI. Evaluation of the arterial and hepatobiliary phases of EOB-MRI would enhance the predictability of VETC.
Authors
- Masashi Tamura (ORCID: https://orcid.org/0000-0002-3762-7144)
- Minoru Kitago (ORCID: https://orcid.org/0000-0002-4909-1199)
- Ken Yamazaki (ORCID: https://orcid.org/0000-0002-7220-7479)
- Michiie Sakamoto
- Yutaka Kurebayashi (ORCID: https://orcid.org/0000-0003-3773-0851)
- Yohei Masugi (ORCID: https://orcid.org/0000-0002-6952-4043)
- Akihisa Ueno (ORCID: https://orcid.org/0000-0001-9428-4128)
- Kosuke Matsuda (ORCID: https://orcid.org/0009-0002-7513-038X)
- Masahiro Jinzaki (ORCID: https://orcid.org/0000-0002-8241-6565)
- Yasushi Hasegawa (ORCID: https://orcid.org/0000-0002-4990-0419)
- Junya Tsuzaki (ORCID: https://orcid.org/0009-0007-2398-5593)
- Yuta Abe (ORCID: https://orcid.org/0000-0002-5840-8901)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Keio University (JP)
- Keio University Hospital (JP)
- International University of Health and Welfare (JP)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1097/hc9.0000000000000593
- Citations
- 10
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 4.04
Funders
- Keio University