Association of leukocyte elastase in semen and seminal plasma with sperm parameters and pregnancy outcomes in male fertility
Although LE serves as a marker for seminal leukocyte concentration, its link to sperm quality and fertility outcomes remains weak and inconsistent. Based on current evidence, LE does not appear to be a reliable diagnostic marker for male infertility. Future studies should focus on standardizing LE measurement techniques and exploring its interaction with other semen parameters to clarify its role in male fertility.
Authors
- Ralf Henkel (ORCID: https://orcid.org/0000-0003-1128-2982)
- Channa Nalin Jayasena (ORCID: https://orcid.org/0000-0002-2578-8223)
- Suks Minhas (ORCID: https://orcid.org/0000-0001-6516-619X)
- Mausumi Das (ORCID: https://orcid.org/0009-0006-0961-0544)
- Maha Gumssani
- Julia Mullaney
- Marie Claire Aquilina
Institutions
- Imperial College Healthcare NHS Trust (GB)
- NIHR Imperial Biomedical Research Centre (GB)
- Henkel (Ireland) (IE)
- Imperial College London (GB)
Publication Details
- Journal
- Endocrine Connections
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1530/ec-24-0571
- Citations
- 1
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.54