Sodium‐Glucose Cotransporter 2 Inhibitors for Mesenchymal–Epithelial Transition Inhibitor‐Induced Edema
The effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on mesenchymal-epithelial transition factor (MET) inhibitor-induced edema remain unclear. In a patient with tepotinib-induced edema and an N-terminal pro-brain natriuretic peptide (NTproBNP) level ≥ 300 pg/mL, the addition of empagliflozin to loop diuretics reduced the edema. This suggests that empagliflozin may be a treatment option for MET inhibitor-induced edema.
Authors
- Nao Muraoka (ORCID: https://orcid.org/0009-0007-3564-039X)
- Toshiaki Takahashi (ORCID: https://orcid.org/0000-0002-8188-2505)
- Tateaki Naito (ORCID: https://orcid.org/0000-0003-4047-2929)
- Keita Miura (ORCID: https://orcid.org/0000-0003-2685-5616)
- Kei Iida (ORCID: https://orcid.org/0000-0001-7130-8705)
- Takuya Oyakawa (ORCID: https://orcid.org/0000-0001-7637-5501)
- Ayano Fujita
Institutions
- Shizuoka Cancer Center (JP)
Publication Details
- Journal
- Thoracic Cancer
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1111/1759-7714.15509
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00