Experimental Study of Electrowetting on Dielectric Combine with Electrochemical Sensor for Depressive Substance Analysis

This research investigated a screen-printed electrowetting on dielectric (EWOD) microchip for depressive substance analysis using a two-part design, a T-junction EWOD containing all the two layers which were a silver electrode and a polydimethylsiloxane (PDMS) dielectric layer. The electrochemical sensor part was at the end of the T -junction EWOD. Three detectors comprised a screen-printing electrode which were graphene/carbon working and counter electrodes, and a silver/silver chloride reference electrode. Both parts of electrode were fabricated using a layer-by-layer screen printing method. The PDMS layer was fabricated using the spin coating method. The electrochemical sensors perform cyclic voltammetry analysis for substances associated with depression. The results showed that electrochemical sensor was a high possibility for depressive substance analysis.