Impact of Hypothermic Perfusion on Immune Responses and Sterile Inflammation in a Preclinical Model of Pancreatic Transplantation
We demonstrated that compared with static cold storage, hypothermic oxygenated perfusion is an effective modality for modulating endothelial function by increasing thrombomodulin expression and decreasing ischemia and vascular endothelial growth factor expression.
Authors
- Julien Branchereau (ORCID: https://orcid.org/0000-0002-8460-9352)
- James Hunter (ORCID: https://orcid.org/0000-0001-9524-0629)
- Delphine Kervella (ORCID: https://orcid.org/0000-0001-8069-6105)
- Thomas Prudhomme (ORCID: https://orcid.org/0000-0003-3601-9339)
- Rutger J. Ploeg (ORCID: https://orcid.org/0000-0001-7801-665X)
- Diego Cantarovich (ORCID: https://orcid.org/0009-0006-0247-966X)
- Mélanie Néel
- Gilles Blancho
- J. Rigaud (ORCID: https://orcid.org/0000-0003-2845-9019)
- Christophe Masset (ORCID: https://orcid.org/0000-0002-7442-2164)
- Peter John Friend (ORCID: https://orcid.org/0000-0003-0841-9685)
- Sarah Bruneau (ORCID: https://orcid.org/0000-0002-1552-0725)
- Martine Minault
- Benoît Mesnard (ORCID: https://orcid.org/0000-0002-3314-1892)
- Stéphanie Le Bas‐Bernardet (ORCID: https://orcid.org/0000-0002-3751-9848)
- M. Hervouet
- Lionel Badet (ORCID: https://orcid.org/0000-0002-9596-0279)
- Etohan Ogbemudia
Institutions
- University of Oxford (GB)
- Hôpital Edouard Herriot (FR)
Publication Details
- Journal
- Transplantation Direct
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1097/txd.0000000000001743
- Citations
- 2
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- Bristol-Myers Squibb
- Astellas Pharma
- Association Française d'Urologie