CLINICAL EFFECTIVENESS OF THE USE OF THE PREPARATION “FERODEV” IN THE PREVENTION AND THERAPY OF IRON DEFICIENCY ANAEMIA IN PIGS

Clinical studies were conducted to determine the effectiveness of the veterinary drug «Ferodev» on suckling piglets and pregnant sows. 1 ml of the drug contains the active ingredient iron (in the form of iron (III) hydroxide dextran complex) – 100,0 mg and excipients - phenol, water for injection. The drug is used for the prevention and treatment of iron deficiency anemia in cattle (calves) and pigs (sows and piglets). The effectiveness of the experimental drug «Ferodev» was determined by the dynamics of biochemical blood parameters of animals and their complete recovery from iron deficiency anemia. The study was conducted in the conditions of the farm «Mriya» of the Rivne district of the Rivne region. The veterinary drug «Ferodev» exhibits anti-anemic properties, in the dosage, method and frequency of application recommended by the manufacturer in the body of suckling piglets and farrowing sows and is not inferior in effectiveness to the comparison drug. The veterinary drug «Ferodev» is not inferior in anti-anemic action to the comparison drug «Bioferon» and has a positive effect on the clinical and biochemical blood parameters of treated piglets (3-5) days old, since on the 14th day, after the use of both drugs, 100% of animals did not observe clinical signs of anemia (decreased appetite, activity, anemia of visible mucous membranes), and their clinical and biochemical blood parameters were restored to the reference level already on the 11th day, after the start of treatment, and stabilized on the 21st day of the experiment. The veterinary drug «Ferodev», in terms of therapeutic efficacy in the prevention of iron deficiency anemia in farrowing sows, is not inferior to the comparison drug «Bioferon» and has a positive effect on the clinical and biochemical blood parameters of the treated animals, since the level of iron deficiency (less than 28,7 μmol/l in blood serum) decreased to the same level of 33,3% in the two experimental groups, 3 weeks before farrowing, and after the second administration, it was completely absent in all animals from both groups, and the remaining clinical and biochemical blood parameters studied also stabilized after the second administration of the drugs (1 week before farrowing). The drug «Ferodev» is recommended for use for the treatment and prevention of iron deficiency anemia in suckling piglets and farrowing sows, according to the leaflet for use developed by «DEVIE» LLC.

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Publication Details

Journal
Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology
Published
2024-12-13
DOI
https://doi.org/10.36359/scivp.2024-25-2.17
Citations
2
Primary Topic
Human Health and Disease
Type
article
Field-Weighted Citation Impact
2.22
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article

CLINICAL EFFECTIVENESS OF THE USE OF THE PREPARATION “FERODEV” IN THE PREVENTION AND THERAPY OF IRON DEFICIENCY ANAEMIA IN PIGS

B. V. Gutyj, B. S. Barylo, T. A. Velesyk, О. А. Кацараба et al.
2 citations
Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology
Human Health and Disease
2.22
article

CLINICAL EFFECTIVENESS OF THE USE OF THE PREPARATION “FERODEV” IN THE PREVENTION AND THERAPY OF IRON DEFICIENCY ANAEMIA IN PIGS

B. V. Gutyj, B. S. Barylo, T. A. Velesyk, О. А. Кацараба, R. M. Sachuk, Izabela Mazur
article en
2 citations

Abstract

Clinical studies were conducted to determine the effectiveness of the veterinary drug «Ferodev» on suckling piglets and pregnant sows. 1 ml of the drug contains the active ingredient iron (in the form of iron (III) hydroxide dextran complex) – 100,0 mg and excipients - phenol, water for injection. The drug is used for the prevention and treatment of iron deficiency anemia in cattle (calves) and pigs (sows and piglets). The effectiveness of the experimental drug «Ferodev» was determined by the dynamics of biochemical blood parameters of animals and their complete recovery from iron deficiency anemia. The study was conducted in the conditions of the farm «Mriya» of the Rivne district of the Rivne region. The veterinary drug «Ferodev» exhibits anti-anemic properties, in the dosage, method and frequency of application recommended by the manufacturer in the body of suckling piglets and farrowing sows and is not inferior in effectiveness to the comparison drug. The veterinary drug «Ferodev» is not inferior in anti-anemic action to the comparison drug «Bioferon» and has a positive effect on the clinical and biochemical blood parameters of treated piglets (3-5) days old, since on the 14th day, after the use of both drugs, 100% of animals did not observe clinical signs of anemia (decreased appetite, activity, anemia of visible mucous membranes), and their clinical and biochemical blood parameters were restored to the reference level already on the 11th day, after the start of treatment, and stabilized on the 21st day of the experiment. The veterinary drug «Ferodev», in terms of therapeutic efficacy in the prevention of iron deficiency anemia in farrowing sows, is not inferior to the comparison drug «Bioferon» and has a positive effect on the clinical and biochemical blood parameters of the treated animals, since the level of iron deficiency (less than 28,7 μmol/l in blood serum) decreased to the same level of 33,3% in the two experimental groups, 3 weeks before farrowing, and after the second administration, it was completely absent in all animals from both groups, and the remaining clinical and biochemical blood parameters studied also stabilized after the second administration of the drugs (1 week before farrowing). The drug «Ferodev» is recommended for use for the treatment and prevention of iron deficiency anemia in suckling piglets and farrowing sows, according to the leaflet for use developed by «DEVIE» LLC.

Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal BiologyVol. 25(2)
Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv (UA), Rivne State University of Humanities (UA), SCIVP of Veterinary Medicinal Products and Feed Additives (UA)
Good health and well-being
Openalex Percentile: Top 10%
Human Health and Disease
2.22
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