Connectivity of the neuronal network for contextual fear memory is disrupted in a mouse model of third‐trimester binge‐like ethanol exposure

These results suggest that CFC is mediated by the limbic memory system and is disrupted following TTAE. Given the increase in CA1 and CA3 activity, a potential hypothesis is that TTAE causes disruptions to memory encoding following day 1 conditioning. Future studies will aim to determine whether this disruption specifically affects the encoding or retrieval of fear memories.

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Publication Details

Journal
Alcohol Clinical and Experimental Research
Published
2024-12-13
DOI
https://doi.org/10.1111/acer.15503
Citations
3
Primary Topic
Neuroscience and Neuropharmacology Research
Type
article
Field-Weighted Citation Impact
0.80

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article

Connectivity of the neuronal network for contextual fear memory is disrupted in a mouse model of third‐trimester binge‐like ethanol exposure

Emerald V. Goranson, David N. Linsenbardt, Glenna J. Chavez, Juhee Patel et al.
3 citations
Alcohol Clinical and Experimental Research
Neuroscience and Neuropharmacology Research
0.80
article

Connectivity of the neuronal network for contextual fear memory is disrupted in a mouse model of third‐trimester binge‐like ethanol exposure

Emerald V. Goranson, David N. Linsenbardt, Glenna J. Chavez, Juhee Patel, Mitchell D. Morningstar, Desna V. Ghatalia, Stefanie S. Mayfield, C. Fernando Valenzuela, Natalie M Reid, Abigale R. Aldrich, Pooja A. Bhakta, Roberto N. Almeida‐Mancero, Edilberto Estrada, Gwen A. Holtzman, Christopher M. Padilla, Joshua Marquez, Andres M. Flores, Katalina M. Lopez, Javier Kelly‐Roman
article en
3 citations

Abstract

These results suggest that CFC is mediated by the limbic memory system and is disrupted following TTAE. Given the increase in CA1 and CA3 activity, a potential hypothesis is that TTAE causes disruptions to memory encoding following day 1 conditioning. Future studies will aim to determine whether this disruption specifically affects the encoding or retrieval of fear memories.

Alcohol Clinical and Experimental ResearchVol. 49(2)
University of New Mexico (US)
National Institute on Alcohol Abuse and Alcoholism, National Institute of General Medical Sciences
Good health and well-being
Openalex Percentile: Top 28%
Neuroscience and Neuropharmacology Research
0.80
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