SWOG S1815: A Phase III Randomized Trial of Gemcitabine, Cisplatin, and Nab-Paclitaxel Versus Gemcitabine and Cisplatin in Newly Diagnosed, Advanced Biliary Tract Cancers
The addition of a taxane in the GAP regimen to the standard gemcitabine-cisplatin regimen did not improve OS in newly diagnosed BTC. More toxicity was encountered with GAP versus GC.
Authors
- Amit Mahipal (ORCID: https://orcid.org/0000-0002-1111-8333)
- Anuj Patel (ORCID: https://orcid.org/0000-0002-7045-6957)
- Imane El Dika (ORCID: https://orcid.org/0000-0003-0067-4198)
- Philip A. Philip (ORCID: https://orcid.org/0000-0002-6513-3491)
- Rachna T. Shroff (ORCID: https://orcid.org/0000-0003-0066-2672)
- Anthony B. El-Khoueiry (ORCID: https://orcid.org/0000-0002-9053-3841)
- Howard S. Höchster (ORCID: https://orcid.org/0000-0002-9893-1529)
- Mitesh J. Borad (ORCID: https://orcid.org/0000-0003-2700-2658)
- Robin Kate Kelley (ORCID: https://orcid.org/0000-0002-1984-2430)
- E. Gabriela Chiorean
- Aaron J. Scott (ORCID: https://orcid.org/0000-0002-0301-3072)
- Khalid Matin (ORCID: https://orcid.org/0000-0001-5368-052X)
- Katherine A. Guthrie (ORCID: https://orcid.org/0000-0001-7257-8280)
- Benjamin Tan (ORCID: https://orcid.org/0000-0003-1838-1182)
- P. Cheema (ORCID: https://orcid.org/0000-0001-9024-9616)
- Milind M. Javle (ORCID: https://orcid.org/0000-0001-9158-0941)
- Renuka Iyer (ORCID: https://orcid.org/0000-0003-3643-8621)
- Sarah Colby
- Gentry Teng King (ORCID: https://orcid.org/0000-0002-7525-8802)
- Laura W. Goff (ORCID: https://orcid.org/0000-0001-6719-1479)
- Jaykumar Thumar (ORCID: https://orcid.org/0000-0001-9882-4574)
- Aparna Kalyan
Institutions
- Rutgers, The State University of New Jersey (US)
- Northwestern University (US)
- University of Southern California (US)
- Roswell Park Comprehensive Cancer Center (US)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Arizona (US)
- Virginia Commonwealth University (US)
- Wayne State University (US)
- Vanderbilt University (US)
- University of Washington (US)
- Washington University in St. Louis (US)
- Yale Cancer Center (US)
- Fred Hutch Cancer Center (US)
- University of California San Francisco Medical Center (US)
- Metro-Minnesota Community Oncology Research Consortium (US)
- Mayo Clinic Hospital (US)
- Dana-Farber/Harvard Cancer Center (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
- University of Arizona Cancer Center
- Vanderbilt-Ingram Cancer Center
- Case Western Reserve University (US)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1200/jco-24-01383
- Citations
- 40
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 22.91
Funders
- Bristol-Myers Squibb
- Celgene
- National Institutes of Health
- National Cancer Institute