O-GlcNAcylation stabilized WTAP promotes GBM malignant progression in an N6-methyladenosine-dependent manner
WTAP plays critical roles in mesenchymal transition of GSCs and formation of TIME, highlighting the therapeutic potential of targeting WTAP and its downstream effectors to enhance the efficacy of immunotherapy.
Authors
- Shaobo Wang (ORCID: https://orcid.org/0000-0001-7759-1687)
- Rongrong Zhao (ORCID: https://orcid.org/0000-0001-5626-1961)
- Caizhi Ma
- Ziwen Pan (ORCID: https://orcid.org/0009-0007-0427-2504)
- Hao Xue
- Yanhua Qi (ORCID: https://orcid.org/0000-0001-5821-7550)
- Qingtong Wang
- Xiaofan Guo (ORCID: https://orcid.org/0000-0002-7220-5094)
- Zijie Gao (ORCID: https://orcid.org/0009-0002-8974-5633)
- Shulin Zhao (ORCID: https://orcid.org/0000-0002-2560-042X)
- Gang Li (ORCID: https://orcid.org/0000-0003-3184-1032)
- Linhong Deng (ORCID: https://orcid.org/0000-0003-1970-8239)
- Boyan Li (ORCID: https://orcid.org/0009-0009-6271-9858)
- Xing Guo (ORCID: https://orcid.org/0000-0001-8431-8590)
- Wei Qiu (ORCID: https://orcid.org/0000-0002-0188-4931)
- Jiawei Qiu
- Weijie Tang
Institutions
- Shandong University (CN)
- Loma Linda University (US)
- Loma Linda University Health Care (US)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1093/neuonc/noae268
- Citations
- 15
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 3.51