Efficacy of Mineralocorticoid Receptor Antagonists on Kidney and Cardiovascular Outcomes in Patients With Chronic Kidney Disease: An Umbrella Review
sMRAs offer benefits in reducing all-cause and cardiovascular mortality and composite CV events in patients treated with dialysis. nsMRAs improve kidney outcomes in patients with nondialysis CKD and DKD but increase hyperkalemia risk.
Authors
- Thunyarat Anothaisintawee (ORCID: https://orcid.org/0000-0003-1002-8536)
- John Attia (ORCID: https://orcid.org/0000-0001-9800-1308)
- Gareth J. McKay (ORCID: https://orcid.org/0000-0001-8197-6280)
- Ammarin Thakkinstian (ORCID: https://orcid.org/0000-0001-9991-386X)
- Porntep Amornritvanich (ORCID: https://orcid.org/0009-0004-2970-4594)
Institutions
- Queen's University Belfast (GB)
- Police General Hospital (TH)
- Ramathibodi Hospital (TH)
- University of Newcastle Australia (AU)
Publication Details
- Journal
- Kidney Medicine
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1016/j.xkme.2024.100943
- Citations
- 4
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Medical Research Council