Preliminary Determination of the Therapeutic Reference Range of Lurasidone in Chinese Patients and Analysis of the Factors Influencing Lurasidone Dose-Corrected Concentrations
The findings of this study indicated that the guideline-recommended therapeutic reference range (15-40 ng·mL -1 ) for lurasidone may not be appropriate, at least for the Chinese population. More extensive therapeutic drug monitoring is recommended for elderly female patients and those receiving co-medication with lurasidone and valproic acid.
Authors
- Yuqing Chen (ORCID: https://orcid.org/0000-0001-9742-2661)
- Dewei Shang (ORCID: https://orcid.org/0000-0001-5546-3393)
- Tao Xiao (ORCID: https://orcid.org/0000-0003-3108-2267)
- Ye Yang (ORCID: https://orcid.org/0009-0000-1286-1631)
- Yuguan Wen
- Zhanzhang Wang (ORCID: https://orcid.org/0000-0003-1949-7312)
- Xiaojia Ni (ORCID: https://orcid.org/0000-0001-6624-5244)
- Eun Mi Song (ORCID: https://orcid.org/0000-0002-2428-1551)
- Haoyang Lu (ORCID: https://orcid.org/0000-0002-7525-5505)
- Lijing Dai (ORCID: https://orcid.org/0000-0002-2015-9145)
Institutions
- Jinan University (CN)
- Shantou University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Yue Bei People's Hospital (CN)
- Guangdong Provincial People's Hospital (CN)
- Guangdong 999 Brain Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Therapeutic Drug Monitoring
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1097/ftd.0000000000001298
- Citations
- 2
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.77