Differential Methylation of CYP11B1 in Girls with High DHEAS Levels and correlation with 11-Oxyandrogen levels: a pilot study

This pilot study proposes the hypothesis that a lower methylation of CYP11B1 may be a mechanism contributing to increased concentrations of 11-oxyandrogens in premature adrenarche and its associated metabolic risk.

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Publication Details

Journal
Hormone Research in Paediatrics
Published
2024-12-13
DOI
https://doi.org/10.1159/000542963
Primary Topic
Sexual Differentiation and Disorders
Type
article
Field-Weighted Citation Impact
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article

Differential Methylation of CYP11B1 in Girls with High DHEAS Levels and correlation with 11-Oxyandrogen levels: a pilot study

Germán Íñiguez, Patricio Miranda, José Luis Santos, Ana Pereira et al.
Hormone Research in Paediatrics
Sexual Differentiation and Disorders
article

Differential Methylation of CYP11B1 in Girls with High DHEAS Levels and correlation with 11-Oxyandrogen levels: a pilot study

Germán Íñiguez, Patricio Miranda, José Luis Santos, Ana Pereira, Verónica Mericq, Esteban Barnafi, Fernándo Rodríguez, Gordon B. Cutler, Diana Ponce
article en

Abstract

This pilot study proposes the hypothesis that a lower methylation of CYP11B1 may be a mechanism contributing to increased concentrations of 11-oxyandrogens in premature adrenarche and its associated metabolic risk.

Hormone Research in Paediatrics
Delta Air Lines (United States) (US), Pontificia Universidad Católica de Chile (CL), University of Chile (CL)
Good health and well-being
Openalex Percentile: Top 80%
Sexual Differentiation and Disorders
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