Intraventricular Medication with or without Ventricular Shunt for Leptomeningeal Metastases with Different Intracranial Pressure: A Single-Center, Large-Scale Retrospective Study
For leptomeningeal metastases, VS not only significantly alleviates symptoms caused by intracranial hypertension but also avoids sudden death for those with severe intracranial hypertension. However, VS placement only does not improve overall survival. IVMs controls effectively leptomeningeal metastases, significantly prolongs survival, enhances quality of life.
Authors
- Jun Xu (ORCID: https://orcid.org/0000-0002-9541-6388)
- Yufang Zhu (ORCID: https://orcid.org/0000-0003-0300-5192)
- Alphonce M. K. Nyalali (ORCID: https://orcid.org/0000-0001-7921-1107)
- Peng Sun (ORCID: https://orcid.org/0009-0006-8394-8973)
- Xinrui Zhang (ORCID: https://orcid.org/0000-0003-0556-0157)
- Yongqiang Hou (ORCID: https://orcid.org/0000-0002-6702-2840)
- Shihao Zhao
- Feng Li
- Xiangji Meng
- Jingwei Cao
Institutions
- Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1016/j.wneu.2024.12.003
- Citations
- 4
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.07