Effects of cladribine on intrathecal and peripheral B and plasma cells
CLADRIPLAS indicates that cerebrospinal fluid oligoclonal bands are not rapidly eliminated in most people with MS. This may be explained by the relative lack of direct cytotoxic action of cladribine on long-lived plasma cells.
Authors
- Sharmilee Gnanapavan (ORCID: https://orcid.org/0000-0003-2817-9922)
- Gavin Giovannoni (ORCID: https://orcid.org/0000-0001-9995-1700)
- David Baker (ORCID: https://orcid.org/0000-0002-8872-8711)
- Gina M. Doody (ORCID: https://orcid.org/0000-0003-0665-6759)
- Alaco Hickey (ORCID: https://orcid.org/0009-0004-5259-8718)
- Kimberley Allen‐Philbey (ORCID: https://orcid.org/0000-0003-1207-8625)
- Maria Papachatzaki
- David W. Holden (ORCID: https://orcid.org/0000-0002-8369-5105)
- Reuben Tooze (ORCID: https://orcid.org/0000-0003-2915-7119)
- Francesca Ammoscato
- Klaus Schmierer (ORCID: https://orcid.org/0000-0002-9293-8893)
- Iman Redha (ORCID: https://orcid.org/0000-0003-1604-940X)
- Helen Lock
- Sofia Grigoriadou (ORCID: https://orcid.org/0000-0002-0265-5014)
- Amy MacDougall (ORCID: https://orcid.org/0000-0002-2900-9602)
- Sophie Stephenson
- Mohammad Aboulwafaali
- Michael Andrews
Institutions
- University of Leeds (GB)
- Queen Mary University of London (GB)
- Barts Health NHS Trust (GB)
- Royal London Hospital (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Khoula Hospital (OM)
Publication Details
- Journal
- Clinical & Experimental Immunology
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1093/cei/uxae116
- Citations
- 3
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Cancer Research UK
- Multiple Sclerosis Society