Leukocyte telomere length decreased the risk of mortality in patients with alcohol-associated liver disease
Our research found that longer LTL improved survival in patients with ALD and decreased CVD and cancer-related mortality. LTL decreased all-cause mortality especially for patients older than 65 years or men. LTL might be a useful biomarker for prognosis among patients with ALD. More prospective studies are needed to assess the relevance between LTL and mortality and explore the underlying mechanisms between them.
Authors
- Hui Guo (ORCID: https://orcid.org/0000-0003-3901-6336)
- Xue Ju
- Jiahong Yi
- Changchuan Jiang (ORCID: https://orcid.org/0000-0002-7392-4154)
- Junyi Duan (ORCID: https://orcid.org/0000-0003-4790-275X)
- Liangping Xia (ORCID: https://orcid.org/0000-0001-7532-4913)
- Yue Zhao
- Wenzhuo He (ORCID: https://orcid.org/0000-0002-7423-4999)
Institutions
- Sun Yat-sen University (CN)
- Jinan University (CN)
- Zhuhai People's Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-12-12
- DOI
- https://doi.org/10.3389/fendo.2024.1462591
- Citations
- 1
- Primary Topic
- Nutritional Studies and Diet
- Type
- article
- Field-Weighted Citation Impact
- 0.54