Discovery and Characterization of Unusual O‐Linked Glycosylation of IgG4 Antibody Using LC‐MS
We discovered a rare glycosylation modification on dupilumab, an IgG4 antibody. The O-linked glycosylation was characterized and localized in the Fab region.
Authors
- Andreas Hoffmann (ORCID: https://orcid.org/0000-0001-8669-3087)
- Chi‐Ya Kao‐Scharf
- Dariusz J. Janecki (ORCID: https://orcid.org/0009-0004-6305-5372)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1002/rcm.9969
- Citations
- 5
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 2.02