Cross-disease transcriptomic analysis reveals DOK3 and PAPOLA as therapeutic targets for neuroinflammatory and tumorigenic processes
DOK3 and PAPOLA play critical roles in both SAH and related neurodegeneration, presenting themselves as potential prognostic biomarkers and therapeutic targets. Notably, DOK3 exhibits potential as an antitumor agent with anti-inflammatory and antioxidative properties, offering therapeutic benefits for both cancer and neuroinflammatory conditions.
Authors
- Wei-Guang Chen
- Xingqiao Wang (ORCID: https://orcid.org/0000-0001-7705-5673)
- Yusong Bian
Institutions
- Qingdao University (CN)
- Yuhuangding Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-12
- DOI
- https://doi.org/10.3389/fimmu.2024.1504629
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00