Prenatal and Early Childhood Exposure to Proton Pump Inhibitors and Antibiotics and the Risk of Childhood Cancer: A Nationwide Population-Based Cohort Study
We did not find evidence that prenatal proton pump inhibitors and antibiotics were associated with overall childhood cancer. However, proton pump inhibitors during early life were associated with an increased risk of childhood cancer, but indication on drug use was not available and confounding by indication may be present.
Authors
- Lars G. Engstrand (ORCID: https://orcid.org/0000-0002-7713-2373)
- Unnur Guðnadóttir (ORCID: https://orcid.org/0000-0002-4663-9921)
- Nele Brusselaers (ORCID: https://orcid.org/0000-0003-0137-447X)
- Anna Wikman (ORCID: https://orcid.org/0000-0003-0937-0887)
- Erika Vlieghe (ORCID: https://orcid.org/0000-0002-4865-3030)
- Emma Fransson (ORCID: https://orcid.org/0000-0001-9010-8522)
- Gustaf Ljungman (ORCID: https://orcid.org/0000-0002-4949-2494)
Institutions
- Uppsala University (SE)
- University of Antwerp (BE)
- Science for Life Laboratory (SE)
- Karolinska Institutet (SE)
- Ghent University (BE)
Publication Details
- Journal
- Drug Safety
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1007/s40264-024-01500-x
- Citations
- 4
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.86
Funders
- Karolinska Institutet
- Vetenskapsrådet