JiangyaTongluo decoction ameliorates tubulointerstitial fibrosis via regulating the SIRT1/PGC-1α/mitophagy axis in hypertensive nephropathy
JYTL decoction may exert renal function protective and anti-fibrosis effects in HN by ameliorating mitochondrial function and regulating the SIRT1/PGC-1α-mitophagy pathway.
Authors
- Yun Fu Zhao (ORCID: https://orcid.org/0000-0002-6357-9422)
- Ziming Yan (ORCID: https://orcid.org/0000-0002-6163-0845)
- Boyang Li (ORCID: https://orcid.org/0000-0002-3154-329X)
- Boya Zhang (ORCID: https://orcid.org/0009-0001-7834-0182)
- Yubo Li (ORCID: https://orcid.org/0000-0003-0455-0969)
- Jianguo Qin (ORCID: https://orcid.org/0000-0002-3981-6862)
- Jia Qi (ORCID: https://orcid.org/0000-0003-4099-2617)
- Han Lin (ORCID: https://orcid.org/0000-0002-0328-7428)
- Yushan Gao (ORCID: https://orcid.org/0000-0001-7383-3327)
- Gaimei Hao (ORCID: https://orcid.org/0000-0001-6513-5449)
- Yiping Wu
- Xiaoyu Zhang (ORCID: https://orcid.org/0000-0002-1752-5482)
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-12-12
- DOI
- https://doi.org/10.3389/fphar.2024.1491315
- Citations
- 8
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.98
Funders
- National Natural Science Foundation of China
- Beijing University of Chinese Medicine
- China Academy of Chinese Medical Sciences