Viability of <i>Plasmodium falciparum</i> parasites in human plasma under different storage conditions
P. falciparum parasites can survive for short durations in human plasma when stored at room temperature, or in refrigerated or frozen conditions at -20°C. However, when stored at -80°C, viable parasites were detected for up to 176 days, the maximum duration for which viability was assessed. In summary, Plasmodium parasites can survive in human plasma under different storage conditions and pose a risk of transfusion-transmitted infection.
Authors
- Clifford T. H. Hayashi
- Anne F. Eder (ORCID: https://orcid.org/0000-0003-2328-626X)
- Victoria Majam
- Sanjai Kumar (ORCID: https://orcid.org/0000-0001-6375-9354)
- Antonina Lavrentieva (ORCID: https://orcid.org/0000-0003-0003-5572)
- Carlos H. Villa (ORCID: https://orcid.org/0000-0002-4632-4751)
- Miranda S. Oakley
Institutions
- Center for Biologics Evaluation and Research (US)
Publication Details
- Journal
- Vox Sanguinis
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1111/vox.13781
- Citations
- 1
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- U.S. Food and Drug Administration