Bronchiectasis in children in a high HIV and tuberculosis prevalence setting

<b>What the study adds.</b> In this retrospective descriptive study of children aged <16 years with chest computed tomography scan-confirmed bronchiectasis in Johannesburg, South Africa (SA), over a 10-year period, we report that a post-infectious cause for bronchiectasis was the most commonly described, and that HIV was an important contributor. A large proportion of children with bronchiectasis in low- and middle-income countries such as SA do not benefit from an extensive work-up for the non-infectious causes of bronchiectasis.<b>Implications of the findings.</b> With improved access to diagnostic techniques, including improvements in early diagnosis and access to treatment for children living with HIV, the aetiology of bronchiectasis is likely to change in the coming years.

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Publication Details

Journal
African Journal of Thoracic and Critical Care Medicine
Published
2024-12-11
DOI
https://doi.org/10.7196/ajtccm.2024.v30i4.1899
Citations
2
Primary Topic
Pneumocystis jirovecii pneumonia detection and treatment
Type
article
Field-Weighted Citation Impact
0.77
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article

Bronchiectasis in children in a high HIV and tuberculosis prevalence setting

Ameena Goga, K Mopeli, Charl Verwey, Diane Gray et al.
2 citations
African Journal of Thoracic and Critical Care Medicine
Pneumocystis jirovecii pneumonia detection and treatment
0.77
article

Bronchiectasis in children in a high HIV and tuberculosis prevalence setting

Ameena Goga, K Mopeli, Charl Verwey, Diane Gray, Ziyaad Dangor, Refiloe Masekela, P Juggernath
article en
2 citations

Abstract

<b>What the study adds.</b> In this retrospective descriptive study of children aged <16 years with chest computed tomography scan-confirmed bronchiectasis in Johannesburg, South Africa (SA), over a 10-year period, we report that a post-infectious cause for bronchiectasis was the most commonly described, and that HIV was an important contributor. A large proportion of children with bronchiectasis in low- and middle-income countries such as SA do not benefit from an extensive work-up for the non-infectious causes of bronchiectasis.<b>Implications of the findings.</b> With improved access to diagnostic techniques, including improvements in early diagnosis and access to treatment for children living with HIV, the aetiology of bronchiectasis is likely to change in the coming years.

African Journal of Thoracic and Critical Care MedicineVol. 30(4)
South African Medical Research Council (ZA), University of Cape Town (ZA), University of the Witwatersrand (ZA), University of Pretoria (ZA), University of KwaZulu-Natal (ZA)
No poverty
Openalex Percentile: Top 24%
Pneumocystis jirovecii pneumonia detection and treatment
0.77
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Bronchiectasis in children in a high HIV and tuberculosis prevalence setting — Ameena Goga, K Mopeli, et al. · African Journal of Thoracic and Critical Care Medicine (2024) | TGRS Research Map | TGRS