Duodenal Organoids From Metabolic Dysfunction-Associated Steatohepatitis Patients Exhibit Absorptive and Barrier Alterations
This study provides evidence that the duodenal epithelium of MASH patients exhibits significant alterations in its nutrition-related and barrier functions. This study sheds light on the intricate dynamics of duodenal epithelial alterations in MASH, highlighting potential therapeutic avenues for restoring intestinal functions.
Authors
- Marjorie Vermeersch
- Anne Lefort
- Morgane Leprovots (ORCID: https://orcid.org/0000-0002-3774-3460)
- Gilles Dinsart (ORCID: https://orcid.org/0009-0002-1449-2854)
- Marie‐Isabelle Garcia (ORCID: https://orcid.org/0000-0003-2147-7003)
- Laurine Verset (ORCID: https://orcid.org/0000-0002-4852-4386)
- David Pérez‐Morga (ORCID: https://orcid.org/0000-0002-7168-1865)
- Alia Hadefi (ORCID: https://orcid.org/0000-0002-6595-2809)
- Daniel Monteyne (ORCID: https://orcid.org/0000-0002-2529-2455)
- Eric Trépo (ORCID: https://orcid.org/0000-0003-0475-3934)
- Claire Liefferinckx (ORCID: https://orcid.org/0000-0002-2046-4051)
- Maryam Marefati
- Christophe Moreno (ORCID: https://orcid.org/0009-0001-5305-2483)
- Jacques Devière (ORCID: https://orcid.org/0000-0002-7993-1945)
- Frédérick Libert (ORCID: https://orcid.org/0009-0004-1429-9936)
Institutions
- Université Libre de Bruxelles (BE)
- Institut Jules Bordet (BE)
Publication Details
- Journal
- Gastro Hep Advances
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1016/j.gastha.2024.100599
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- Fonds Erasme